Classification of enzyme
Classification of enzyme:
Classification of the enzyme is very important to study about Enzymes and their reaction. The Enzymes are classified according to the reaction they catalyze. The classification is shown below:
Oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule to another molecule. The transfer of electron means the transfer of hydride of a hydrogen atom.
Transferases are enzymes that catalyze the transfer of a functional group from a donor molecule to an acceptor molecule. Here Group transfer reactions are occurred.
Hydrolases are a class of enzymes that catalyze the hydrolysis of a chemical bond.
For example, an enzyme that catalyzed the following reaction is a hydrolase:
A–B + H2O → A–OH + B–H.
Lyase is an enzyme that catalyzes the breaking (an “elimination” reaction) of various chemical bonds by means other than hydrolysis and oxidation, often forming a new double bond or a new ring structure.
Ligase is an enzyme that can catalyze the joining of two large molecules by forming a new chemical bond (Formation of C─C, C─S, C─O, and C─N bonds by condensation reactions coupled to ATP cleavage).
Isomerases are enzymes that catalyze the isomerization of a molecule. In other words, they facilitate the transfer of specific functional groups
Enzymes are classified according to the type of reaction they catalyze:
Classification of Enzymes
|Transferases||Transfer groups of atoms||Alanine transferase|
|Lyases||Add atoms/remove atom to/from a double bond||Pyruvate decarboxylate|
|Isomerases||Rearrange atoms||Maleate isomerase||
|Ligases||Use ATP to combine molecules||Acetyl-Co A synthetase||
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